GA@net Entry

University of Halle-Wittenberg, Institute for Pharmacy, RG Pharmacognosy


Hoher Weg 8
Zip/Post Code
Halle (Saale)

Personal data

Contact person
Dr. Raphael Reher
Role in Organization
Junior Researcher / Postdoc

Main Area of Expertise

NP Drug discovery, NP chemistry
Main facilities and/or core expertise
2020-current: Habilitand (MLU Halle-Wittenberg, Institute for Pharmacy, RG Niedermeyer) 2018-2020: Postdoctoral Researcher (Scripps Institution of Oceanography, UCSD, Gerwick lab) 2015-2018: PhD (University of Bonn, Institute for Pharmaceutical Biology, RG König) 2013-2015: M.Sc. Drug Research (University of Bonn, Institute for Pharmaceutical Biology, RG König) since 09/2013: Licensed Pharmacist
Main output/products/publications
1. Reher R*, Kim H*, Zhang C*, … , Cottrell GW, Gerwick WH. “A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Product” J. Am. Chem. Soc. 2020, 142, 9, 4114-4120. 2. Dührkop K*, Felix-Nothias L*, Fleischauer M, Reher R, Ludwig M, Hoffmann MA, … , Dorrestein PC, Böcker S “Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra” Nat Biotechnol 39, 462–471 (2021). 3. Crüsemann M* and Reher R* et al. “Heterologous expression, biosynthetic studies and ecological function of the selective Gq-signaling inhibitor FR900359.” Angew. Chem. Int. Ed. 2018. 57, 836–840. 4. Reher R et al. "Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359" J. Nat. Prod. 2018, 81, 7, 1628-1635. 5. Reher R* and Kühl T* et al., “Deciphering specificity determinants for FR900359-derived Gαq inhibitors based on computational and structure-activity studies” ChemMedChem, 2018, 13, 1634-1643.
Fields of interest
Scientific collaboration