GA@net Entry
University of Halle-Wittenberg, Institute for Pharmacy, RG Pharmacognosy
Organization
Address
Hoher Weg 8
Zip/Post Code
6120
City
Halle (Saale)
Country
Germany
Personal data
Contact person
Dr. Raphael Reher
Phone
ORCID-ID
https://orcid.org/0000-0002-5858-1173
Role in Organization
Junior Researcher / Postdoc
Main Area of Expertise
Areas
NP Drug discovery, NP chemistry
Main facilities and/or core expertise
2020-current: Habilitand (MLU Halle-Wittenberg, Institute for Pharmacy, RG Niedermeyer)
2018-2020: Postdoctoral Researcher (Scripps Institution of Oceanography, UCSD, Gerwick lab)
2015-2018: PhD (University of Bonn, Institute for Pharmaceutical Biology, RG König)
2013-2015: M.Sc. Drug Research (University of Bonn, Institute for Pharmaceutical Biology, RG König)
since 09/2013: Licensed Pharmacist
Main output/products/publications
1. Reher R*, Kim H*, Zhang C*, … , Cottrell GW, Gerwick WH. “A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Product” J. Am. Chem. Soc. 2020, 142, 9, 4114-4120.
2. Dührkop K*, Felix-Nothias L*, Fleischauer M, Reher R, Ludwig M, Hoffmann MA, … , Dorrestein PC, Böcker S “Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra” Nat Biotechnol 39, 462–471 (2021). https://doi.org/10.1038/s41587-020-0740-8
3. Crüsemann M* and Reher R* et al. “Heterologous expression, biosynthetic studies and ecological function of the selective Gq-signaling inhibitor FR900359.” Angew. Chem. Int. Ed. 2018. 57, 836–840.
4. Reher R et al. "Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359" J. Nat. Prod. 2018, 81, 7, 1628-1635.
5. Reher R* and Kühl T* et al., “Deciphering specificity determinants for FR900359-derived Gαq inhibitors based on computational and structure-activity studies” ChemMedChem, 2018, 13, 1634-1643.
Fields of interest
Scientific collaboration
