Job Opportunities

One year Post-doctoral position in Marine Natural Products Chemistry (analytical/organic chemistry) at Institut de Chimie de Nice (ICN)

UMR7272, CNRS, Université Côte d’Azur (UCA)

Duration: 12 months

Starting date: no later than September/October 2023
Location: ICN, UCA, 28 avenue de Valrose, 06108, Nice, France

Experience: less than 2 years after PhD

Application deadline: 15/05/2023

Applications should be sent to Prof Mohamed MEHIRI, combined as one pdf file, and should include:

• cover letter
• Full CV including your scientific skills and all your research experiences
• 2 pages max. of a summary of your research experiences (PhD/Post-doc)
• contact information for at least 2 referees (recommendation letters should be sent directly to M. MEHIRI)

Topic: Marine macro- and microorganisms represent an under-explored source of new natural products which exhibit in situ several biological activities (cytotoxic, antibiotic, antifungal, antifouling, etc.). Marine natural products have often original structures, different from those of the metabolites of the terrestrial environment, and exhibit potent pharmacological activities with novel mechanisms of action. They could therefore be used to address unmet medical needs such as anticancer and antibiotic resistance.

In this context, the purpose of the post-doctoral project is the development of new marine natural products from untapped marine organisms. The selected candidate will be in charge to conduce the following tasks:

• Extraction, fractionation, isolation and structural characterization (NMR 1D and 2D, MS, UV, IR, CD) of marine natural products, notably from sponges and/or cultivated marine fungi
• Synthesis of small molecules selected for their structural singularities and biological properties. The project is published in its most general version and will be detailed to the selected candidate.

We seek to hire an outstanding researcher at a post-doc level with strong and solid skills/experiences in experimental analytical chemistry (chromatography, 1D and 2D NMR, HRMS, IR, UV, CD…), organic chemistry, and natural products chemistry.