GA@net Entry

University of Yaounde

Pharmacotoxicology, Preclinical drug discovery, Phytochemistry, Phytopharmaceutical research, Molecular biology.


Ngoa Ekelle
Zip/Post Code
Research Institution

Personal data

Contact person
Role in Organization
Junior Researcher / Postdoc

Main Area of Expertise

NP Drug discovery, NP chemistry
... please specify
Main facilities and/or core expertise
Pharmaco- toxicology, Preclinical drug discovery, Phytochemistry, Phytopharmaceutical research, Molecular biology.
Main output/products/publications
1. Emmanuel Mfotie Njoya, Paul Fewou Moundipa, and Timo H. J. Niedermeyer (2021). Codiaeum variegatum (L.) Rumph. ex A. Juss. (Euphorbiaceae): An overview of its botanical diversity, traditional uses, phytochemistry, pharmacological effects and perspectives towards developing its plant-based products. Journal of Ethnopharmacology 277: 114244. 2. Azubuike Peter Ebokaiwe*; Emmanuel Mfotie Njoya*; Yuwen Sheng; Zhonghui Zhang; Li Sheng; Zongyuan Zhou; Zhe Qiang; Peng Ting; Ahmed A Hussein; Guolin Zhang; Xiaoxia Lu; Lin Li; Fei Wang (2020). Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells. Toxicology and Applied Pharmacology 404, 115203. (*equal contribution).3. Jean-Bosco Jouda*, Emmanuel Mfotie Njoya*, Serge Alain Tanemossu Fobofou, Zong Yuan Zhou, Zhe Qiang, Céline Djama Mbazoa, Wolfgang Brandt, Guo-lin Zhang, Jean Wandji, Fei Wang (2020). Anti-inflammatory activity of new polyketide metabolites from the endophytic fungus Phomopsis sp. CAM212, through the down regulation of ERK/IκBα signalling pathways. Planta Medica 86 (13/14): 1032 -1042. (*equal contribution).4. Emmanuel Mfotie Njoya, Jacobus N. Eloff, Lyndy J. McGaw (2018). Acetone leaf extract of Croton gratissimus selectively inhibits cancer cell proliferation and induces caspase 3/7 activation with additional good antioxidant and anti-inflammatory potential. BMC Complementary and Alternative Medicine 18 :305. 5. Mfotie Njoya E, Weber C, Hernandez-Cuevas NA, Hon C-C, Janin Y, Melanie F. G. Kamini, Paul F. Moundipa, Nancy Guillén (2014). Bioassay-Guided Fractionation of Extracts from Codiaeum variegatum against Entamoeba histolytica Discovers Compounds That Modify Expression of Ceramide Biosynthesis Related Genes. PLoS Neglected Tropical Diseases, 8(1): e2607.
Fields of interest
Scientific collaboration